Industry luminaries from Gartner, McKinsey, and regulatory bodies converge in this chapter to candidly address GenAI's thorniest challenges in risk and compliance. Foremost are explainability deficits, where "black-box" models hinder auditability, and escalating cyber threats from AI-generated deepfakes. Experts decry fragmented regulations, with 70% advocating global standards akin to GDPR for AI. Perspectives also tackle talent shortages and ethical dilemmas, like algorithmic bias perpetuating inequities. Solutions proposed include interdisciplinary upskilling, federated learning for privacy, and collaborative sandboxes for testing. Overcoming these is pivotal for GenAI's trustworthy proliferation.